Inhibition of the STAT3 Signaling Pathway Contributes to the Anti-Melanoma Activities of Shikonin
BackgroundMalignant melanoma is an extremely aggressive and metastatic cancer, and highly resistant to conventional therapies.Signal transducer and activator of transcription 3 (STAT3) signaling promotes melanoma development and progression, which has been validated as an effective target in melanoma treatment.Natural bempresas.com naphthoquinone s